This chapel dates back to the late 13th century, although its original layout was drastically altered between 1683 and 1699 during the renovation of the Bovio Palace. At that time, the building’s length was reduced to allow for the widening of Via Mercanti.

The chapel follows the ancient east-west orientation, with the altar and apse facing the sunrise—a symbolic alignment that evokes the light of the divine.

The building has two entrances reflecting a classical and understated architectural style. A particularly curious detail is the stone lion-shaped water spout near the top of the façade.

The main altar—from 1606—is enhanced by a sculpted table and an elegant late-Renaissance backdrop. This frames a painting of the Deposition of Christ, surrounded by the mourning women, Joseph of Arimathea and Saint Catherine of Alexandria, to whom a second altar is dedicated. The painting shows influences from the Workshop of Alfonso de Cordoba.